Introduction: Ozone is an unstable allotropic form of oxygen and is applied through different methods in the treatment of various diseases. Bactericidal, fungicidal, virustatic, immunomodulating, analgesic and anti-inflammatory effects are among the many beneficial effects of ozone. One of the other uses of ozone is for the treatment or at least relief of back pain. Ozone therapy is performed as direct administration in the form of an oxygen-ozone mixture into the intervertebral disc, usually at a concentration 27 mcg/ml We aimed to investigate the efficiency of intradiscal ozone therapy in patients with recurrent disc herniation and experiencing pain. The values are compared with non-operated patients receiving primary ozone therapy.
Patients and Methods: Between December 2012 and February 2016, 101 patients data who were admitted to our clinic for ozone therapy, screened and 56 patients data enrolled into
our study. Age ranged between 18 and 65. Patients were divided into two groups as Group A (non-operated patients, n: 32) and Group B (recurrent patients, n: 24). Results of intradiscal ozone therapy were compared between two groups and on admission, at the 1st, 3rd, 6th, and 12th months with visual analogue scale (VAS) and Oswestry Disability Index (ODI).
Results: When the baseline values are compared with the values of the first, third, sixth and twelveth months as an indication of efficiency of the intradiscal ozone therapy, at all time points there was statistically significant improvement with p values of <0.001.
Conclusion: Intradiscal ozone injection may be accounted among the minimally invasive alternative options to conventional open redo-surgery in patients with recurrent disc herniation with considerable promising outcomes not being inferior to primary ozone therapy in non-operated patients.
Anahtar Kelimeler: Back pain; Disc hernia; Surgery; Intradiscal ozone therapy, redo surgery, failed back surgery syndrome, ozone .